Meaning

noun (usually preceded by `in') a detail or point

noun paying particular notice (as to children or helpless people)

noun (usually plural) a polite expression of desire for someone's welfare

originFrom Middle English regard, regarde, reguard, from Anglo-Norman reguard, from regarder, reguarder. Attested in Middle English starting around the mid 14th century. Piecewise doublet of reward; compare also guard, ward, guardian, and so on.

Etymology from Wiktionary, CC BY-SA 3.0