Meaning

noun a large, flat, thin case for carrying loose papers or drawings or maps; usually leather

noun a set of pieces of creative work collected to be shown to potential customers or employers

noun a list of the financial assets held by an individual or a bank or other financial institution

originFrom Italian portafoglio; cognate with French portefeuille (“folder, wallet”), from Latin portāre (“to carry”) and folium (“sheet”). The meaning "collection of responsibilities" came by extension in the 1930s.

Etymology from Wiktionary, CC BY-SA 3.0