8 letters · 10 points in Scrabble
adjective holding that only material phenomena can be known and knowledge of spiritual matters or ultimate causes is impossible
adjective uneducated in general; lacking knowledge or sophistication
originUltimately from Latin nesciēns (“ignorant, unknowing”), the present participle of nesciō (“to don’t know, to be ignorant of”).
Etymology from Wiktionary, CC BY-SA 3.0