Meaning

noun an external body part that projects from the body

noun an extreme condition or state (especially of adversity or disease)

noun the greatest or utmost degree

originFrom Middle English extremite, from Old French extremité, from Latin extrēmitātem (“extremity; border, perimeter; ending”), from extrēmīs (“furthest, extreme”) + -itās (ultimately from Proto-Indo-European *-teh₂ts (suffix forming nouns indicating a state of being); see extreme. Extrēmīs is derived from exter (“external, outward”) (ultimately from Proto-Indo-European *h₁eǵʰs (“out”)) + -issimus…

Etymology from Wiktionary, CC BY-SA 3.0