Meaning

noun a disease that is constantly present to a greater or lesser degree in people of a certain class or in people living in a particular location

noun a plant that is native to a certain limited area

adjective of or relating to a disease (or anything resembling a disease) constantly present to greater or lesser extent in a particular locality

originFrom Ancient Greek ἐν (en, “in”) + δῆμος (dêmos, “people”) + -ic. Possibly via Ancient Greek ἔνδημος (éndēmos, “among one's people, at home, native”) and/or French endémique. By surface analysis, en- + demic.

Etymology from Wiktionary, CC BY-SA 3.0