Meaning

verb deprive of strength or vigor

verb remove the testicles of a male animal

adjective having unsuitable feminine qualities

originFrom Medieval Latin ēmasculātus, perfect passive participle of ēmasculō (“to emasculate”) (see -ate (verb-forming suffix)), from ē(x)- (“out, from, apart”) + masculus (“male, masculine”) + -ō (first conjugation verb-forming suffix), further from mās (“a man, a male”) + -culus (diminutive suffix).

Etymology from Wiktionary, CC BY-SA 3.0