Meaning

noun transactions (sales and purchases) having the objective of supplying commodities (goods and services)

noun the United States federal department that promotes and administers domestic and foreign trade (including management of the census and the patent office); created in 1913

noun social exchange, especially of opinions, attitudes, etc.

originBorrowed from Middle French commerce, from Latin commercium. Doublet of comess.

Etymology from Wiktionary, CC BY-SA 3.0