6 letters · 8 points in Scrabble
noun an area of skin that is thick or hard from continual pressure or friction (as the sole of the foot)
noun bony tissue formed during the healing of a fractured bone
noun (botany) an isolated thickening of tissue, especially a stiff protuberance on the lip of an orchid
originBorrowed from Latin callum (“hard skin”). Displaced Old English wearr.
Etymology from Wiktionary, CC BY-SA 3.0