9 letters · 14 points in Scrabble
noun an area of skin that is thick or hard from continual pressure or friction (as the sole of the foot)
noun devoid of passion or feeling; hardheartedness
originFrom Middle English callosite, collositee, calosite, from Anglo-Norman calosité (compare Old French chalosité), from Latin callōsitās, equivalent to callous + -ity.
Etymology from Wiktionary, CC BY-SA 3.0